Local Point-of-Care (POC) Diagnostic Enzyme Designer, Rapid TB Radar & Africa-First Genome R&D
Solve cold-chain reagent dependency and European AI model bias. We orchestrate ESM3, Evo 2, AlphaFold 3, AlphaGenome (1M bp window), and Botanic1 to design patent-free local POC diagnostic enzymes, predict TB drug resistance in seconds, and map conserved 3D vaccine epitopes across African strains.
How It Works With Your Equipment & Sovereign Cloud Switchboard
Local POC Diagnostic Enzymes (PROD-03)
Engineers thermostable, patent-free Bst polymerase (DOTDR-Bst-SA4, Tm = 71.8°C) and Cas12a diagnostic scaffolds that require zero cold chain for South African lateral-flow and isothermal POC strips.
TB & Hospital AMR Resistance in Seconds
Quantifies 3D steric occlusion in M. tuberculosis rpoB, katG, inhA, gyrA, and atpE pockets in seconds (11.4s end-to-end) to rank optimal drug regimens.
Africa-First 98.5% Non-Coding Genome & Vaccine R&D (PROD-04)
Global AI models are trained predominantly on European genomes. DotDr validates models on African genomes—including the 98.5% non-coding regulatory DNA—and maps conserved 3D surface epitopes across Southern African TB/HIV/pathogen lineages.
100% Client IP & Source Code Ownership
Under our R160,000 2-Week Custom AI Sprint, your institution retains 100% ownership of custom sprint code and engineered sequences to use freely across your research.
Procurement, LIMS & Regulatory Answers
Do we have to upload our own wet-lab data to evaluate PROD-03 and PROD-04?
No. All 4 DotDr products include pre-loaded, zero-upload live benchmarks (DOTDR-POC-ENZ-201, DOTDR-AMR-RADAR-202, DOTDR-VAC-AFR-301, DOTDR-REG-AFR-302) that your scientists can inspect today using your R5,000 Compute Grant Voucher.
Who owns the IP generated during a Custom 2-Week Sprint?
You do. Your institution receives 100% source code and deliverable ownership to use freely across your research, with associated project hosting fees billed monthly based on 3rd-party cloud consumption.